by Eric Christianson | Jun 11, 2025 | Drug Interaction Case Studies and Education For Pharmacists
Trimethoprim-sulfamethoxazole (Bactrim) is a commonly prescribed antibiotic for urinary tract and other infections. However, it’s also associated with several clinically significant drug interactions that can lead to serious patient harm if overlooked. Here are my top...
by Eric Christianson | Apr 18, 2021 | Medication and Disease State Clinical Pearls For Pharmacists, Neurology, Pain, and Musculoskeletal Medication and Disease State Clinical Pearls
Brand to generic drug changes can occur due to demands by insurance companies. These changes are often forced due to the low costs of generic medications compared to brand name products but are there certain classes of medications where brand to generic changes may be...
by Eric Christianson | Nov 6, 2019 | Drug Interaction Case Studies and Education For Pharmacists
In the case scenario below, I discuss the implications of the verapamil phenytoin interaction. JS is a 38-year-old male who has been on phenytoin for seizure prophylaxis for several years. He reports to his primary care provider complaining of severe headaches. He is...
by Eric Christianson | Jul 21, 2019 | Drug Interaction Case Studies and Education For Pharmacists
Phenytoin drug interactions are common in our polypharmacy patient. The key is to monitor patients closely as well as carefully reviewing the medication list when a new medication is going to be started or changed. While there are numerous drug interactions with this...
by Eric Christianson | Apr 21, 2019 | Drug Interaction Case Studies and Education For Pharmacists
In the case scenario below, I outline a case where the Bactrim phenytoin interaction leads to phenytoin toxicity. An 81-year-old female has a history of GERD, OA, and seizures. She hasn’t been feeling the best and reports fatigue and painful urination. She has...
