Statins are one of the most commonly prescribed medications to help reduce cholesterol and reduce the risk of cardiovascular events like heart attack and stroke. I’ve been asked the question a few different times about why we should choose a hydrophilic versus a...
P-Glycoprotein inhibitors can and do affect the concentrations of other drugs. I will be honest in that when I think about drug interactions, it isn’t the first thing that comes to mind. This gut transporter can impact clinical care and influence drug decisions....
Pharmacokinetics is a scary word for many in the medical field. The best way that I remember being taught pharmacokinetics is to think about what the body does to the drug. If we understand pharmacokinetics, we can definitely optimize our patient’s medications...
98 y/o female had a long history of seizures was treated with Dilantin (phenytoin) 100 mg twice daily. The Dilantin level was routinely drawn every 6 months and had been in the 6-10 range for quite sometime (normal total level is 10-20, but there are multiple...
Many patients and healthcare professionals may not realize that different formulations of a product can have very different pharmacokinetics. Why does pharmacokinetics matter? An 88 year old patient was receiving Namenda (memantine) 5 mg in the morning and 10 mg in...
