I don’t recall learning about oxycodone pharmacokinetics in school. Cut me some slack, maybe I was gone that day? Or maybe my memory is fading? It’s actually pretty complicated and drug interactions and pharmacogenomics can play a significant role in how a...
The kidney plays many vital roles in the body. One of those roles is to eliminate medications and their metabolites. When the kidney is not functioning well, drugs are eliminated from the body at a slower rate and can accumulate. Those higher drug concentrations can...
In this article, we break down the most important ketamine clinical pearls. Ketamine (ketamine hydrochloride) is FDA approved for general anesthesia in diagnostic and surgical procedures that do not require skeletal muscle relaxation. It has been used on its own or as...
Opioids are commonly used in clinical practice. Selection on these agents can often be confusion. We’ve outlined some of the most important pharmacokinetic, pharmacogenomic, and dosage form clinical pearls in the table below. For easier reading, we have also...
Lorazepam and clonazepam are both from the benzodiazepine family. I see them both used in clinical practice on a regular basis. While their pharmacology actions are essentially identical, there are some pharmacokinetic, dosage form, and indication differences you...