The kidney plays many vital roles in the body. One of those roles is to eliminate medications and their metabolites. When the kidney is not functioning well, drugs are eliminated from the body at a slower rate and can accumulate. Those higher drug concentrations can...
The American Diabetes Association released their 2022 Diabetes Guidelines update. While I wouldn’t call the changes earth-shattering, there are some items in relation to pharmacotherapy that I feel are really important to note. The patient population that I work...
CA is a 58-year-old female with CKD. Her CrCL today is 45 mL/min and stable sCr of 1.3 mg/dL. She complains of muscle aches that started a couple of weeks ago and that her doctor said she can’t use NSAIDs, even though the Tylenol doesn’t completely help the pain. She...
A compelling indication is simply another reason (typically a disease state) as to why you choose a medication. Compelling indications in diabetes are increasingly important in medication selection in diabetes. I lay out some of those reasons below. Metformin...
Metformin is the go-to first-line medication in type 2 diabetes. While drug interactions aren’t incredibly common with its use, we should be aware of OCT inhibition and the potential effects that this might cause. Under normal circumstances, this isn’t...
