Thiazide diuretics are commonly are one of the most commonly used classes of antihypertensive agents. They carry many adverse effects. Some can be a nuisance while others can be more serious. In this blog post, I’ll run down the most common thiazide diuretic...
In this hypertension case study, JD is a 64-year-old male who has a history of hypertension, GERD, gout, diabetes, constipation, and sexual dysfunction and presents with the following medication list. Hydrochlorothiazide 25 mg daily Amlodipine 5 mg daily Omeprazole 20...
If you work with patients at all, you’ll see some of the most common antihypertensive agents used on a daily basis. The reason they are used so frequently is because they do not tend to have many significant drug interactions. However, some do exist and I wanted...
Is as needed (PRN) allopurinol appropriate? I have seen as-needed (PRN) orders for allopurinol in practice. It has been rare, but it has happened. Did I like it? No. Allopurinol helps to lower uric acid levels. Allopurinol inhibits xanthine oxidase which is an enzyme...
Lowering uric acid is the key to reducing gout flares. Both allopurinol (podcast) and febuxostat are effective at performing this task. However, there are some considerations you need to be aware when deciding to utilize allopurinol versus febuxostat. I’ll break...