In the case scenario below, I outline a case where the Bactrim phenytoin interaction leads to phenytoin toxicity. An 81-year-old female has a history of GERD, OA, and seizures. She hasn’t been feeling the best and reports fatigue and painful urination. She has...
The SSRI and NSAID interaction kind of drives me crazy. It is one of those interactions where you don’t really know how seriously to take it. SSRI has the potential to impact platelet function. NSAIDs have the potential to impact platelet function. The SSRI and...
The tacrolimus and azole drug interaction is a concerning one that needs to be monitored. In this case, the drug interaction was actually used to the benefit of the patient. I’m greatly appreciative of this guest post/case from Amanuel Tseggai, PharmD, BCPS!...
The Celexa and Nexium interaction is a challenging one. As a clinical pharmacist, I don’t want to create a bunch of other work or switch agents when medication therapy is working and justified. I feel like we (physicians, NP’s, PA’s as well) often...
P-Glycoprotein inhibitors can and do affect the concentrations of other drugs. I will be honest in that when I think about drug interactions, it isn’t the first thing that comes to mind. This gut transporter can impact clinical care and influence drug decisions....