In this case study, we discuss a situation where a drug causes a higher pH in the stomach. The elevated pH from an antacid can impact the absorption of other drugs. A 44-year-old female presents to the clinic with Strep throat. Her current medications include...
There are numerous types of drug interactions. I outline some of the most common ways that drugs can affect the concentrations and activity of other drugs. Opposing Effects Many drugs will work on various receptors throughout the body. To use as an educational point,...
Metformin is the go-to first-line medication in type 2 diabetes. While drug interactions aren’t incredibly common with its use, we should be aware of OCT inhibition and the potential effects that this might cause. Under normal circumstances, this isn’t...
In the case scenario below, I discuss the implications of the verapamil phenytoin interaction. JS is a 38-year-old male who has been on phenytoin for seizure prophylaxis for several years. He reports to his primary care provider complaining of severe headaches. He is...
When the NOACs (sometimes referred to as DOACs) first came out they were heavily promoted as having fewer drug interactions compared to warfarin. This is true, but please remember that “fewer drug interactions” doesn’t mean “no drug...
