Earlier this month the FDA approved Rexulti (Brexpiprazole) for the treatment of agitation in patients with dementia due to Alzheimer’s. Originally approved as an atypical antipsychotic used for schizophrenia, or an adjunct therapy for major depressive disorder,...
Trazodone (podcast) is part of a class of antidepressants known as triazolopyridines. I am seeing trazodone for dementia related agitation in my practice and wanted to get a quick review of how solid the evidence is. Let’s start with the basics. Trazodone is...
I stumbled into this article a while ago regarding Nuedexta off-label fraud for behavioral issues involving dementia patients in long term care facilities. It makes me sad and frustrated. I’d like to make a couple of points. Nuedexta Off-Label Evidence in...
In keeping it real today, I wanted to share my top 5 medications that worsen dementia. This list is totally anecdotal based upon my experience and the frequency with which I see these medications used in clinical practice. Without further ado, here are my top 5...
Donepezil (Aricept) is an acetylcholinesterase inhibitor that is used to help manage symptoms of dementia. I get asked quite a few questions about dementia and, more specifically, dementia-related medications. Here’s a recent question I received; If a patient is...