Last night of Narcweek! Hope you all enjoyed it! Methadone is a drug you may see once in a while for treatment of pain. There are definitely some prescribers that are more comfortable using this drug than others. It is an opioid similar to fentanyl, morphine, oxycodone, etc… It does have a little bit of a unique mechanism versus other opioids. The way methadone works, it may actually be more beneficial for neuropathic type pain than other traditional opioids. So in an individual where the standard neuropathic medications may have failed(gabapentin, duloxetine, etc.,) it may be a consideration especially if the provider feels a opioid is necessary. I think one of the things that discourages its use is the challenging transition to another opioid if that needs to be done. The conversion depends upon how high the dose is which can make conversion tricky!