Glyburide in Kidney Disease

Glyburide in Kidney Disease

Using glyburide in kidney disease is not recommended.  It has a longer half life and may have a little more potent effect in kidney disease.  A significant challenge to figure out is if patients are doing well on their current dose, should we change it?  In this...
Using Gabapentin in Chronic Kidney Disease

Using Gabapentin in Chronic Kidney Disease

I appreciate the fantastic guest post from Amanuel Tseggai, Pharm.D., BCPS! There are plenty of clinical considerations when it comes to gabapentin.  Here’s a scenario of using gabapentin in chronic kidney disease. A 42 year old African American man with a history of...
My Pet Peeves – Management of UTI’s

My Pet Peeves – Management of UTI’s

It’s no secret that I work with a lot of geriatric patients.  These things have been on my mind lately about the management of UTI’s, so just wanted to share them.   With rare exception, asymptomatic bacteriuria (ASB) should not be treated.  ASB is...
5 Clinical Pearls on Alpha Blockers

5 Clinical Pearls on Alpha Blockers

Alpha blockers are indicated for both hypertension and BPH.  Here’s a few clinical pearls on alpha blockers that you need to know! Alpha blockers in females:  I remember a urologist getting frustrated with pharmacists who would always question why he was using...
New Incontinence Medication Case (Myrbetriq – mirabegron)

New Incontinence Medication Case (Myrbetriq – mirabegron)

An 88 year old female was struggling with incontinence. Upon a nursing assessment, this patient was frequently incontinent throughout the day and night. For her Congestive Heart Failure, the patient needed increased doses of diuretics which obviously can make things...
Gabapentin and Kidney Function Changes

Gabapentin and Kidney Function Changes

This elderly patient had been on a dose of (Neurontin) gabapentin 600 mg three times daily for peripheral neuropathy. Over time, the patient’s kidney function had been declining and was diagnosed with chronic kidney disease. Family had begun to notice that the...