Timolol is an effective medication for reducing intraocular pressure in patients with glaucoma. The recommended starting dose is one drop of timolol 0.25% ophthalmic solution in the affected eye(s) twice daily. It is a non-selective beta-blocker. Ophthalmic...
As previously discussed, mirtazapine can be more sedating at lower doses. Mirtazapine has a high affinity for the H1 (histamine) receptor. This histamine blockade is thought to increase appetite and sedation. Weight gain with mirtazapine can be advantageous or a...
Many providers will not encounter patients with HIV very often, but it may become more commonplace now as HIV therapy has improved dramatically as well as life expectancy in patients with the disease. It is important for providers to meet these patients’ HIV-related...
Direct-acting oral anticoagulants (DOACs; also called NOACs – novel oral anticoagulants) are an increasingly popular alternative to warfarin. Meanwhile, the number of obese patients requiring anticoagulation is also increasing. Because the landmark studies that...
Mirtazapine is commonly used in elderly patients with depression who are also suffering from insomnia. Mirtazapine is often chosen because it is much safer than benzodiazepines, “z-drugs”, and antipsychotics. The mechanisms of mirtazapine (podcast episode on the...
While not incredibly common, medications can cause dysregulation of our body’s thermoregulation process and cause a rise in core temperature in the presence of normal core body temperature which leads to hyperthermia. Before we get to the drugs that cause...