Parkinson’s disease (PD) has long presented challenges in medication delivery. A staple in more advanced disease control, carbidopa-levodopa requires multiple daily dosing with supratherapeutic levels leading to dyskinesias and subtherapeutic concentrations leading to...
Doxepin is a tricyclic antidepressant first approved for the treatment of depression in 1969 by the FDA. Tricyclic antidepressants are famous for their anticholinergic adverse effects including sedation and have been replaced by better-tolerated medications as...
Technology continues to impact disease state management in remarkable ways. Monitoring of patients with diabetes is no exception. Both the American Diabetes Association and American Association of Clinical Endocrinologists/American College of Endocrinology make light...
Here’s a case scenario where the clinical outcome may have hinged on taking ziprasidone with or without food. KD is a 33-year-old male who was diagnosed with schizophrenia. Olanzapine and risperidone were the first antipsychotics that were tried to help...
While many who don’t understand pharmacology consider the SSRIs to be interchangeable, significant consequences can result if we don’t pay attention to the risk of drug interactions. When looking at the SSRIs and CYP enzymes, it is critical to remember...
Tramadol is used in clinical practice, but it does have numerous drug interactions that you should be aware of. When reviewing a medication list or when a patient starts a new medication, here are some of the items that I think about when monitoring for tramadol drug...
