A 78 year old patient with a past medical history of bipolar disorder, dementia with aggressive behaviors, hypertension, and neuropathy was being evaluated and was initiated on Trileptal (oxcarbazepine) to try to help with neuropathy. He had been tried on numerous...
Citalopram is a very commonly used antidepressant and is part of the Selective Serotonin Reuptake Inhibitor (SSRI) class. SSRI’s do have the potential to contribute to SIADH (basically a reduction in sodium levels in the body). The case: A 68 year old female...
62 year old male who has been struggling with depression and anxiety is place on an SSRI, sertraline (Zoloft) 50 mg daily. No response is noted within a few weeks, so it was planned to titrate up on the dose. He was titrated to a dose of 200 mg daily over the course...
When I’ve had students with me, they will often ask about multiple serotonin related drugs and risk of serotonin syndrome. A classic example of this is a patient on an SSRI and Tramadol. This combination is used frequently in practice. Serotonin syndrome is...
88 y/o female who’s had some difficulty with pain management. She was on scheduled Tylenol (acetaminophen) 1,000 mg twice daily as well as Ultram (tramadol) 50 mg every 6 hours as needed. She had brought up the complaint about her osteoarthritis to her...
A 68 year old female was having difficulty with some anxiety throughout the day but more problematic to the patient was that she could not sleep at night. Multiple different non-drug interventions were tried, but none seemed to make any difference. Trazodone was...
