When the NOACs (sometimes referred to as DOACs) first came out they were heavily promoted as having fewer drug interactions compared to warfarin. This is true, but please remember that “fewer drug interactions” doesn’t mean “no drug...
Lithium has numerous clinical pearls that are essential to remember. Of all the educational points about this medication, you must remember some of these important lithium drug interactions. The list below is not an all-inclusive list, just ones that more commonly...
As I’m working on 2020 updates for all of our board certification study material, I couldn’t help but recognize that I did not have a dedicated lecture on pharmacogenomics. Below I discuss how genetic alterations in CYP2D6 activity can affect two commonly...
Enzyme inducers most frequently reduce the concentrations of other drugs. This can ultimately lead to treatment failure. In rare situations (i.e. prodrugs), starting an enzyme inducer can potentially raise concentrations of the active metabolite and increase the risk...
Phenytoin drug interactions are common in our polypharmacy patient. The key is to monitor patients closely as well as carefully reviewing the medication list when a new medication is going to be started or changed. While there are numerous drug interactions with this...
The albuterol beta-blocker interaction is real and is significant. But how significant is it? What questions should you ask yourself? Which Beta-Blocker We Talkin’ Bout? The very first question I would assess is which beta-blocker are we talking about as not all...
