In this case study, I highlight the clinical impact that the ciprofloxacin and zolpidem interaction can have on a patient. JS is a 58-year-old female with a history of insomnia and takes zolpidem 10 mg at bedtime every night. She has recently been diagnosed with a...
Beta-blockers are a class of medication that is frequently used for cardiac and cardiovascular purposes. Selectivity and evidence of benefit often guide selection, but one thing that may get overlooked is beta-blocker interactions in relation to CYP enzymes. Not all...
Fluticasone is one of the most commonly used inhaled corticosteroids for the management of asthma and other respiratory conditions. I’ve encountered drug interactions frequently with fluticasone because it is metabolized by CYP3A4. I’ve seen this...
Apixaban (Eliquis) is an anticoagulant used for stroke prophylaxis in atrial fibrillation, and treatment and prophylaxis of DVT/PE. Its use has grown exponentially since it was first FDA-approved. When it comes to patient medications, apixaban is not exempt from...
There are literally thousands of drug interactions so I had my work cut out to try to narrow down the list to the top 10. In this post, I outline my list of the top 10 drug interactions. This is based on a combination of my experience, the frequency of the...
CYP2D6 is an important pathway for the breakdown of certain medications. There are also some less common cases of medications that are prodrugs and activated by this enzyme. It is important to know some of these commonly used medications and how they may impact...
