Rifampin is an enzyme inducer. What does this mean? Basically it causes enzymes in the body to chew up material (drugs, chemicals etc.) more quickly. A while back I posted about how changing this drug’s dosing, starting the medication, or discontinuing the medication...
I’ve had a request to explain a couple of the most common drug/food interactions I see. There were two that immediately popped into my mind: 1. Statins(Zocor-simvastatin, Lipitor-atorvastatin, etc.) are some of the most widely used drugs in the US and there is...
I had a patient a while back struggling with ongoing depression symptoms, fatigue, and constipation indicative of symptoms of hypothyroidism. In this case, a couple of different antidepressants Remeron (mirtazapine) and Zoloft (sertraline) had been tried without any...
Question: Is Tylenol safe to use with Coumadin? Tylenol (acetaminophen) is generally considered as one of the safest pain medications when used appropriately. With that being said, we have to remember that there is always risk when taking medications along with...
I’ve got another example involving an interaction with Coumadin that you may not have thought about before. Most often when I discuss Coumadin interactions with students, the first thought in most people’s minds is what drug did we add that caused the INR to go up. ...
Coumadin and NSAIDs(Advil, Aleve, Nabumetone, etc.) probably one of the worst drug-drug interactions, in fact the AMDA lists it as one of its top ten in long-term-care/geriatrics. http://www.amda.com/tools/clinical/m3/topten.cfm – NSAIDs can cause issues with...
