CNS depressant interactions are everywhere. There are so many patients (typically patients with mental health and pain concerns) on multiple medications that can cause CNS sedation/depression. TCA’s, Sleepers, Opioids, muscle relaxants, Benzo’s, and on...
Drug interactions and how to manage them can be very challenging and frustrating. Let’s take a look at the amitriptyline and tramadol interaction. Different sources report different potential interactions. Medscape, Drugs.com both report different interactions...
We must remember the topiramate and birth control interaction! The case: A 33 year old female has had an increase in the frequency of migraines over the last few months. She has had about 6 episodes in the last month. These episodes have lasted nearly 24 hours...
Tumeric and Apixaban – Guest Post by Amanuel Tseggai A 72 year old man was newly diagnosed with atrial fibrillation and started on therapeutic dose of Enoxaparin after he was admitted to a hospital. Four days into his treatment with Enoxaparin his primary care...
Drug interactions can make medication management challenging. Here’s a classic case demonstrating the rifampin and phenytoin interaction. A 47 year old patient with diabetes and seizure disorder is diagnosed with new onset osteomyelitis. The patient’s...
MAOI’s (mono-amine oxidase inhibitors) can be used for depression. With that stated, they have a significant number of clinical pearls that limit there use. MAOI’s and drug interactions are two terms that you should lump together. Very rarely do I see...