P-Glycoprotein inhibitors can and do affect the concentrations of other drugs. I will be honest in that when I think about drug interactions, it isn’t the first thing that comes to mind. This gut transporter can impact clinical care and influence drug decisions....
Apixaban (Eliquis) is a somewhat newer anticoagulant. While it is tempting to utilize the “set it and forget it” mindset with dosing, we must remember that there are a few reasons that we might have to make apixaban dose adjustments. Apixaban dose...
Here I will discuss the propranolol and ciprofloxacin interaction by presented a brief case scenario. A 59 year old female with a 40 year history of smoking a pack per day presents today, complaining of worsening respiratory status. She is having a lot of dyspnea. ...
Managing schizophrenia can be incredibly challenging. Drug interactions are a major factor in that challenge. Olanzapine is broken down by CYP1A2. Smoking causes induction of the CYP1A2 enzyme. The olanzapine smoking cessation interaction is one that we should...
Iron drug interactions are very common. Use of iron products like ferrous sulfate is also extremely common. Two diseases that iron deficiency can cause is anemia and restless leg syndrome. There are iron drug interactions that can reduce the effectiveness of iron. ...
Here’s a case scenario involving the Prozac Wellbutrin interaction. A 64 year old male has severe depression. He is currently on Remeron 15 mg once daily, Prozac 80 mg once daily, and Abilify 10 mg once daily. He has been tried on just about every other SSRI...
