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Changing Glimepiride to Glipizide…to Rock the Boat or Not?
With the recent changes in the Beers Criteria, glimepiride has now been added to the list of sulfonylureas to avoid. Glipizide is the preferred agent if a sulfonylurea is to be used. This begs the...
Med List Review
A 72-year-old male has a past history of heart failure with reduced ejection fraction, chronic kidney disease, hypertension, diabetes, intermittent claudication, and osteoarthritis. His current...
Top 5 Medications That Worsen Dementia
In keeping it real today, I wanted to share my top 5 medications that worsen dementia. This list is totally anecdotal based upon my experience and the frequency with which I see these medications...
Top 5 Medications to Avoid In Heart Failure
I have seen the prescribing cascade happen in clinical practice far too many times! One of those classic examples is heart failure. A patient is placed on a new medication that contributes to edema...
Recommendations to Physicians – Why You’re Not Convincing Anyone
I've written thousands of recommendations to physicians and other healthcare providers throughout my career. I've gotten over the fear of failure so to speak, but there's always still a little doubt...
Carbamazepine Interactions – What to do About Them?
I'm working on a new book that I'm super excited about! I'm writing a book on drug interactions and hope to finish by the end of the year! I'm tackling the top 200 drugs plus those I consider very...
Insomnia Polypharmacy
Insomnia is a sneaky condition that can lead to polypharmacy. Many of the medications used in the management of insomnia can work for a short period of time, but I've seen so many cases where the...
2020 Pharmacist Job Market Outlook
I'm saddened for some of my friends and colleagues who've recently lost their job. The recent move by HealthPartners in my own state hits close to home. HealthPartners is closing up 30 retail...
OCT Inhibition and How It Affects Metformin
Metformin is the go-to first-line medication in type 2 diabetes. While drug interactions aren't incredibly common with its use, we should be aware of OCT inhibition and the potential effects that...
Verapamil Phenytoin Interaction – Management Pearls
In the case scenario below, I discuss the implications of the verapamil phenytoin interaction. JS is a 38-year-old male who has been on phenytoin for seizure prophylaxis for several years. He...