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SGLT2 Inhibitors Comparison Table – Clinical Application
Sodium-glucose co-transporter 2 inhibitors (SGLT2s) are becoming popular treatments for type 2 diabetes mellitus. While typically classified as diabetes medications, there is more and more research...
5 Drugs That Cause Pulmonary Toxicity
Pulmonary toxicology involves the airways, lung parenchyma, mediastinum, pleura, pulmonary vasculature, and the neuromuscular system based on the route of exposure to the offending agent and the...
New ISH 2020 Blood Pressure Guidelines
Recently, the International Society of Hypertension released its 2020 blood pressure guidelines. Their guidelines do vary a little bit from the 2017 ACC/AHA guidelines that were put out a few years...
Bedtime Cocktail – Gabapentin, Ropinirole, and Tramadol
I often find patients on numerous bedtime cocktails and this is often a situation where medications were slowly added over time for recurring symptoms of the same syndrome. A 79-year-old female at a...
How To Manage An Out Of Range Digoxin Level
On a previous post, I discussed some issues surrounding digoxin use in CHF. In this post, I wanted to cover strategies for managing an out of range digoxin level. Digoxin is a drug that we can and...
Codeine – It’s Complicated
I received a question about codeine and what to expect from its use. When I was first learning pharmacy back in the late 2000s, I saw a lot of codeine. Most frequently, I remember significant use of...
Can I Take Sulfonylureas With a Sulfa Allergy
Many patients are labeled as having a “sulfa allergy”. This is typically going to be from a reaction to sulfa antibiotics (i.e. sulfamethoxazole). Sulfonylureas are one of the drug classes that have...
2020 Gout Guidelines – Important Takeaways
Recently, the American College of Rheumatology released new 2020 gout guidelines. In these guidelines, there are 42 recommendations that reflect new clinical evidence since the release of the 2012...
Recommended Separation for Nitrates and PDE-5 Inhibitors
Avanafil, sildenafil, tadalafil, and vardenafil are PDE-5 inhibitors available in the USA and indicated for erectile dysfunction. PDE-5 inhibitors prevent the breakdown of cGMP and it is also...
Can I Mix Nebulized Medications? Including Revefenacin
The administration procedure for inhalation therapy with nebulizers can be very lengthy and time-consuming. Because of this, many providers, pharmacists, nurses, and respiratory therapists could...