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Cholestyramine and Warfarin – Not What You Might Think
When most healthcare professionals think about drug interactions, we tend to think about an issue arising when a medication is added to the regimen. A perfect example is the warfarin Bactrim...
Sinemet 10/100 – Why You Shouldn’t Use It
Parkinson's disease can be very debilitating and not understanding how medications should be dosed can compound the problem. Let's review the pharmacology briefly and why you need to be careful with...
Not All Statins Interact With Grapefruit Juice
Drug food interactions are common and there can be significant negative consequences from these interactions. A common misconception amongst healthcare professionals who may not have as much...
Paroxetine in Pregnancy – Why not?
If you are a healthcare professional, inevitably, questions about the use of antidepressants in pregnancy come up in clinical practice. Why is paroxetine generally avoided in pregnancy? The primary...
Free Pharmacology Course – No Strings Attached
I can't thank you all enough for the support and as always I like to provide some free resources (in addition to the blog and podcast) along the way! I've just recently released a free pharmacology...
Ophthalmic Timolol and Hypotension – More Than What Meets The Eye
Timolol is an effective medication for reducing intraocular pressure in patients with glaucoma. The recommended starting dose is one drop of timolol 0.25% ophthalmic solution in the affected eye(s)...
Weight Gain With Mirtazapine – The Heavy Truth
As previously discussed, mirtazapine can be more sedating at lower doses. Mirtazapine has a high affinity for the H1 (histamine) receptor. This histamine blockade is thought to increase appetite and...
Appropriate Lab Monitoring in HIV
Many providers will not encounter patients with HIV very often, but it may become more commonplace now as HIV therapy has improved dramatically as well as life expectancy in patients with the...
To Use DOACs in Obesity or Not?
Direct-acting oral anticoagulants (DOACs; also called NOACs – novel oral anticoagulants) are an increasingly popular alternative to warfarin. Meanwhile, the number of obese patients requiring...
Mirtazapine For Insomnia – Are You Using It Correctly?
Mirtazapine is commonly used in elderly patients with depression who are also suffering from insomnia. Mirtazapine is often chosen because it is much safer than benzodiazepines, “z-drugs”, and...