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Top 5 CYP2C19 Drug Interactions

Top 5 CYP2C19 Drug Interactions

Here's a list of some of the most common CYP2C19 drug interactions that I have seen in clinical practice. Citalopram and Omeprazole Interaction Omeprazole can significantly increase the...

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Ziprasidone With Or Without Food?

Ziprasidone With Or Without Food?

Here's a case scenario where the clinical outcome may have hinged on taking ziprasidone with or without food. KD is a 33-year-old male who was diagnosed with schizophrenia. Olanzapine and...

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SSRIs and CYP Enzymes

SSRIs and CYP Enzymes

While many who don't understand pharmacology consider the SSRIs to be interchangeable, significant consequences can result if we don't pay attention to the risk of drug interactions. When looking at...

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Constipation Prescribing Cascade

Constipation Prescribing Cascade

At its worst, constipation can be a very serious issue in some patients and at best be a significant nuisance. Here's a classic example of the constipation prescribing cascade. A 72-year-old female...

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Tramadol Drug Interactions

Tramadol Drug Interactions

Tramadol is used in clinical practice, but it does have numerous drug interactions that you should be aware of. When reviewing a medication list or when a patient starts a new medication, here are...

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Senna and Loperamide Scheduled

Senna and Loperamide Scheduled

Somedays I scratch my head more than others...today was one of those days. Seeing Senna and loperamide scheduled together made me scratch it REAL hard. A 77-year-old male was complaining of...

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5 OTCs That Cause GI Issues

5 OTCs That Cause GI Issues

Over-the-counter medications play a huge role in modern healthcare. In my practice, I've had caught many adverse effects simply by reviewing the entire medication list and asking about OTCs. Here...

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