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Top 5 CYP2C19 Drug Interactions
Here's a list of some of the most common CYP2C19 drug interactions that I have seen in clinical practice. Citalopram and Omeprazole Interaction Omeprazole can significantly increase the...
Ziprasidone With Or Without Food?
Here's a case scenario where the clinical outcome may have hinged on taking ziprasidone with or without food. KD is a 33-year-old male who was diagnosed with schizophrenia. Olanzapine and...
SSRIs and CYP Enzymes
While many who don't understand pharmacology consider the SSRIs to be interchangeable, significant consequences can result if we don't pay attention to the risk of drug interactions. When looking at...
Constipation Prescribing Cascade
At its worst, constipation can be a very serious issue in some patients and at best be a significant nuisance. Here's a classic example of the constipation prescribing cascade. A 72-year-old female...
BCPS Recertification By Exam Pros and Cons
Many have asked me what are the pros and cons of doing BCPS recertification by exam. Here are my thoughts on this. BCPS Recertification by Exam: The Pros If you are anything like me, I learn best...
Tramadol Drug Interactions
Tramadol is used in clinical practice, but it does have numerous drug interactions that you should be aware of. When reviewing a medication list or when a patient starts a new medication, here are...
Senna and Loperamide Scheduled
Somedays I scratch my head more than others...today was one of those days. Seeing Senna and loperamide scheduled together made me scratch it REAL hard. A 77-year-old male was complaining of...
5 OTCs That Cause GI Issues
Over-the-counter medications play a huge role in modern healthcare. In my practice, I've had caught many adverse effects simply by reviewing the entire medication list and asking about OTCs. Here...
Why We Would and Wouldn’t Use Ziprasidone
Looking at the adverse effect profile of second-generation antipsychotics is critical to medication selection in clinical practice. You should definitely know the general list of adverse effects of...
GLP-1 Agonists And The Prescribing Cascade
The GLP-1 Agonists have grown significantly in their popularity and there are good reasons for that increase in use. They promote weight loss which is a big problem in the majority of our type 2...