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Diuretics And The Prescribing Cascade
Diuretics are a medication that I see used on a daily basis. I also encounter these medications causing adverse effects. With adverse effects comes the potential for providers to add medications to...
Heart Failure Guideline Updates in 2021
There are a few important heart failure guideline updates in the works to the American College of Cardiology’s Heart Failure Guidelines, last published in 2013. Prior to the full guideline release,...
Lithium Toxicity Due To Thiazide Diuretic
It is critical to remember that lithium toxicity can result due to numerous possible drug interactions. Here's a case scenario where lithium toxicity was caused by a thiazide diuretic. KE is a...
Medications For Weight Loss – Clinical Breakdown
Obesity is a major risk factor for many comorbidities (hypertension, dyslipidemia, osteoarthritis, sleep apnea, heart disease, type 2 diabetes) and increases all-cause and cardiovascular mortality....
Semaglutide For Weight Loss – STEP 1 Trial
A new treatment for chronic weight management is likely on the way. In a recent trial, investigators looked at semaglutide for weight loss. The final results of the STEP1 trial (Semaglutide...
Rytary (Carbidopa-Levodopa ER) in Parkinson’s Disease
Parkinson’s disease (PD) has long presented challenges in medication delivery. A staple in more advanced disease control, carbidopa-levodopa requires multiple daily dosing with supratherapeutic...
Doxepin Pharmacodynamics: Indication or Adverse Effect?
Doxepin is a tricyclic antidepressant first approved for the treatment of depression in 1969 by the FDA. Tricyclic antidepressants are famous for their anticholinergic adverse effects including...
Indication Guides Dosing – Primidone and Escitalopram
There are numerous examples of where the indication guides dosing. It is important as a pharmacist to remember this when you see unusual doses. I wanted to share a couple of examples that I came...
Medications That Interfere With Continuous Glucose Monitoring
Technology continues to impact disease state management in remarkable ways. Monitoring of patients with diabetes is no exception. Both the American Diabetes Association and American Association of...
Cyclobenzaprine And The Prescribing Cascade
Cyclobenzaprine (podcast episode) is a skeletal muscle relaxant that is most commonly used for muscle spasms and back pain. It definitely has some potential adverse effects that I have seen lead to...