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Why “Stable” Leads to Polypharmacy – 3 Case Examples

Why “Stable” Leads to Polypharmacy – 3 Case Examples

by Eric Christianson | May 3, 2026 | Polypharmacy Cases And The Prescribing Cascade

I’ve been collecting examples of situations where a patient is “stable”, and a provider doesn’t want to change medications. Stable is good, right? It is, but it can also lead to providers not wanting to reduce medications and change anything....
Clonidine Versus Guanfacine – Comparison in ADHD

Clonidine Versus Guanfacine – Comparison in ADHD

by Eric Christianson | Apr 29, 2026 | Psychiatry and Addiction Medication and Disease State Clinical Pearls

Clonidine and guanfacine are both alpha-2 adrenergic agonists used in the treatment of ADHD, but they behave differently enough in clinical practice that they are not truly interchangeable. In this article, we will compare and contrast clonidine versus guanfacine in...
5 Reasons To Get Rid Of PRNs

5 Reasons To Get Rid Of PRNs

by Eric Christianson | Apr 26, 2026 | Polypharmacy Cases And The Prescribing Cascade

As-needed medications (PRNs) are a common part of life for geriatric patients in long-term care and assisted living facilities. They can make things more complicated as well, and I would implore you to review these medications frequently to ensure that they are truly...
Bowel Regimens – Curbing Polypharmacy

Bowel Regimens – Curbing Polypharmacy

by Eric Christianson | Apr 22, 2026 | Gastrointestinal Case Studies

One of the most common (and easily fixable) medication mismatches I see in practice involves bowel regimens that outlive their original purpose. This is a great example of how deprescribing can reduce pill burden and prevent unnecessary adverse effects. Bowel Regimens...
Beta-Blockers In Asthma; The Best and Worst

Beta-Blockers In Asthma; The Best and Worst

by Eric Christianson | Apr 19, 2026 | Respiratory Medication and Disease State Clinical Pearls

Beta-blockers have long been approached with caution in patients with asthma due to their potential to provoke bronchospasm and blunt the effects of rescue inhalers. This risk is largely driven by receptor selectivity. In this article, we will break down the best and...
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  • Why “Stable” Leads to Polypharmacy – 3 Case Examples
  • Clonidine Versus Guanfacine – Comparison in ADHD
  • 5 Reasons To Get Rid Of PRNs
  • Bowel Regimens – Curbing Polypharmacy
  • Beta-Blockers In Asthma; The Best and Worst

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Subscribe to the Blog!

Enjoy the blog?  Over 6,000 pharmacy loving folks follow the blog, why aren't you? Subscribe now and get a free gift as well!

Recent Posts

  • Why “Stable” Leads to Polypharmacy – 3 Case Examples
  • Clonidine Versus Guanfacine – Comparison in ADHD
  • 5 Reasons To Get Rid Of PRNs
  • Bowel Regimens – Curbing Polypharmacy
  • Beta-Blockers In Asthma; The Best and Worst

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